Abstract

Risk Scores for Stroke Prevention in Patients with Non-Valvular Atrial Prevention: Is it Time to Put Parameters of Left Atrial Appendage Morphology and Function Into Clinical Practice?

Highlights

  • Overall, one-third of thromboembolic events originated from the heart

  • Eight additional cross-sectional studies utilizing this classification for Left atrial appendage (LAA) morphology in 2,210 patients (6 with computed tomography (CT) and 2 with transesophageal echocardiography (TEE)), found a significant

  • The possibility of simple characterization with TEE patients with less-thrombogenic LAA anatomy, was associated with less significant clinical events compared with patients with “thrombogenic non-chicken LAA morphology” (11.2% vs. 25.2% - p = 0.005)

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Summary

Introduction

One-third of thromboembolic events originated from the heart. Left atrial appendage (LAA) and its anatomic complexity has been implicated in 90% of cases of thrombus formation and cardioembolic events in patients with non-valvular atrial fibrillation (AF). In 2012, Di Biase et al.;[2] published a retrospective study of 932 patients with AF and computed tomography (CT)/magnetic resonance imaging (MRI) classification of four different types of LAA morphologies: chicken wing, cactus, windsock and cauliflower. Eight additional cross-sectional studies utilizing this classification for LAA morphology in 2,210 patients (6 with CT and 2 with TEE), found a significant

Results
Conclusion
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