Abstract

Objective:To determine the risk profile of chronic kidney disease (CKD) patients.Methods:This is an observational cross sectional study involving 130 patients for which data was collected prospectively.. Sixty five subjects with an estimated glomerular filtration rate (eGFR) below 120 ml/min/1.73 m2 were recruited via random sampling technique from nephrology clinic in a tertiary nephrology referral center. Medical history, demographic data, urinary and serum biochemistry tests were obtained.Results:Most of the CKD patients who were referred to the nephrology clinic were asymptomatic. The most common laboratory abnormalities noted among CKD patients were proteinuria, anaemia and hyperkalaemia. Advancing age, pre-existing morbidities such as diabetes mellitus, hypertension and overweight are characteristics that are strongly associated with the referred CKD patients.Conclusions:Most of the referred CKD patients are in advanced age with diabetes, hypertension and overweight. Majority of the CKD remained asymptomatic despite in the advance stage of CKD. This strongly calls for cost effective screening for population at risk.

Highlights

  • Chronic kidney disease (CKD) is a major health problem as one of the non-communicable diseases

  • All the patients who were diagnosed as chronic kidney disease (CKD) were randomly selected from Serdang Hospital nephrology clinic based on pre determined randomized technique of recruitment of one patient per every three patients who attended the clinic to a sample of size of 65

  • Demographic data such as age, gender, ethnicity, height, body mass index, aetiology of CKD, co-morbidities diabetes, hypertenson, cerebral vascular event and laboratory data such as blood pressure, creatinine, haemoglobin, HbA1C, serum calcium, serum phosphate, status of hepatitis B and hepatitis C, GFR, presence or absence of proteinuria and signs and symptoms related to CKD were collected

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Summary

Introduction

Chronic kidney disease (CKD) is a major health problem as one of the non-communicable diseases. The prevalence of chronic kidney disease (CKD) is estimated at > 500 million individuals globally and this is partly due to increased prevalence of hypertension, diabetes and metabolic syndrome.[1] A main challenge for targeting chronic kidney disease (CKD) is the heterogeneity of its causes, comorbidities and outcomes. Mohd Zharif Fikri A.S. 1-3: Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 43400, Serdang, Malaysia

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