Abstract
Great advances have been made in oncology with regard to diagnostics, prognostics and therapeutics. However, dosing of chemotherapy in most cancers is still being based on the estimation of body surface area (BSA) [log (body surface in m2)=0.425log (weight in kg)+0.725log (length in cm)+1.8564]. BSA fails, however, to standardize the marked inter-patient variation in pharmacokinetics for most cytotoxic drugs [1]. If not adjusted for, overweight and obese individuals receive higher relative (to tumor burden) doses of chemotherapy compared with normal or underweight individuals.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
