Abstract

smoking and serum total cholesterol and glucose levels. The six colors on each chart corresponded to levels of probability of CVD-related death. Unfortunately, these charts predicted only fatal CVD and were based on a limited number of predictive markers measured 30 years ago. The Japan Lipid Intervention Trial (J-LIT) charts also show absolute and relative risk for primary and secondary CHD, derived from a 6-year prospective study of about 50000 participants; however, the data are from a cohort of patients with mild hypercholesterolemia and under simvastatin treatment. 8 Risk charts for CHD and stroke from the Jichi Medical School (JMS) cohort study are also available; these were based on a 10-year prospective study of about 12000 participants living in 12 communities, but the surveyed communities were limited to rural areas. 9,10

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