Risk Of Transmission Of Tick-Borne Diseases By Blood Transfusion

Abstract

Abstract The fear of blood transfusion-borne infections has been a problem since the beginning of the blood therapy era. One of the phases of all infectious diseases, including those transmitted by ticks, is the incubation period, during which there are no clinical symptoms due to the presence of microorganisms in the blood. For this reason, blood drawn from an infected donor can be a potential source of infection for the recipient at this time. Literature data show that there are no documented reports of the possibility of transmitting B. burgdorferi infection (Lyme etiological factor) to healthy man by blood transfusion. However, cases of transfusions of such infections as babesiosis, anaplasmosis, rickettsiosis, and fever, bartonellosis have been reported. Tick-borne infections are not included in the criteria for permanent (except tularemia) or temporary disqualification for blood donor candidates and for contraindications for blood sampling. Tests for routine detection of tick-borne pathogens in blood therapy are also not used. Therefore, knowledge of the dynamics of the phases of these diseases, periods of infectivity and occurring in the blood in conjunction with medical history, physical examination and the results of auxiliary diagnostic tests are of fundamental importance for the safety of blood recipients. 1. Introduction. 2. Spirochetes infections. 2.2. Lyme borreliosis. 2.2. Borrelia myiamotoi infections. 3. Spotted Fever Group rickettsioses. 4. Human granulocytic anaplasmosis 5. Bartonella sp. Infections. 6. Babesiosis. 7. Summary