Abstract

The occurrence of status epilepticus (SE) after the initial diagnosis of epilepsy was determined in a prospective community-based cohort study of 613 children at Montefiore Medical Center, Bronx, NY; Yale Medical School, New Haven, CT; and BIOS/NIU, DeKalb, IL.

Highlights

  • In a previous study by the current group of authors, status epilepticus (SE) was the first seizure in 38 (11%) of 342 children followed for a mean of 72 months after a first idiopathic unprovoked seizure (Shinnar S, et al Dev Med Child Neurol 1995;37: 116)

  • 13 (2.1%) died, and the risk of dying was greater in children who had previous SE (5/56 [8.9%]) vs 8/557 [1.4%] who did not (P=0.0002)

  • Children who experienced SE during follow-up were less likely to be in 3-year remission (19.6% vs 65.3%; PO.OOOl) and much more likely to have intractable seizures (47.4% vs 8.9%; P

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Summary

Introduction

In a previous study by the current group of authors, SE was the first seizure in 38 (11%) of 342 children followed for a mean of 72 months after a first idiopathic unprovoked seizure (Shinnar S, et al Dev Med Child Neurol 1995;37 (suppl 72): 116 (abstract)). The occurrence of status epilepticus (SE) after the initial diagnosis of epilepsy was determined in a prospective community-based cohort study of 613 children at Montefiore Medical Center, Bronx, NY; Yale Medical School, New Haven, CT; and BIOS/NIU, DeKalb, IL. In those with no SE before initial diagnosis, the risk of SE during follow-up was 14% in the symptomatic etiology group vs 2.6% in the idiopathic group.

Results
Conclusion
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