Abstract

Background: Ischemic stroke is more commonly occurs in smokersObjective: The purpose of the present study was to estimate the risk of smoking with ischemic stroke in Bangladesh. Methodology: This case control study was carried out in the Department of Biochemistry at Dhaka Medical College, Dhaka, Bangladesh from January 2014 to December 2014. Thepatients presented with ischemic stroke, age ranges from 18 to 65 years of both sexes were taken as cases. Age and sex matched healthy individuals were selected as controls. History was taken from both cases and controls regarding smoking habit and duration of smoking. Results: Inthis study 42% of case group and 11% control group were smoker (p=0.032) and the mean duration of smoking was 22.14±10.58 years and 4.45±2.58 years for those groups respectively. The odd ratio (OR) was 2.56(95%.0718 to 6.1501). Conclusions: Smoking is significantly associated with ischemic stroke.

Highlights

  • Worldwide ischemic stroke is a major public health problem and a leading cause of mortality and morbidity in developing countries [1]

  • A number of risk factors that have been shown to be associated with stroke are age, high blood pressure, diabetes mellitus, hypercholesterolemia, previous history of stroke or, Transient Ischemic Attack (TIA), obesity and dietary factors, atrial fibrillation and cigarette smoking [4]

  • A total number of 100 subjects were recruited for this study of which 50 ischemic stroke patients were considered as cases and the rest 50 were taken as healthy controls

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Summary

Introduction

Worldwide ischemic stroke is a major public health problem and a leading cause of mortality and morbidity in developing countries [1]. Smoking is a major modifiable risk factor for atherosclerotic disease [5]. Tobacco smoking is a leading modifiable global disease risk factor. Ischemic stroke is more commonly occurs in smokers Objective: The purpose of the present study was to estimate the risk of smoking with ischemic stroke in Bangladesh. Thepatients presented with ischemic stroke, age ranges from 18 to 65 years of both sexes were taken as cases. History was taken from both cases and controls regarding smoking habit and duration of smoking. Results: Inthis study 42% of case group and 11% control group were smoker (p=0.032) and the mean duration of smoking was 22.14±10.58 years and 4.45±2.58 years for those groups respectively.

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