Abstract
Background Since the advent of combination antiretroviral therapy (cART), several studies have described an increase in the incidence of Hodgkin lymphoma (HL). This increase has been postulated to be linked with immunologic mechanisms occurring at cART initiation. Relationships between the CD4 cell count and the risk of HL have also been investigated. Our study aimed to evaluate the risk of HL by use of cART and its duration.
Highlights
Since the advent of combination antiretroviral therapy, several studies have described an increase in the incidence of Hodgkin lymphoma (HL)
Our study aimed to evaluate the risk of HL by use of combination antiretroviral therapy (cART) and its duration
Materials and methods From the French Hospital Database on HIV (FHDHANRS CO4), a large prospective hospital cohort, we studied the incidence of HL in 1992-2007 according to the duration of cART exposure: no cART and year
Summary
Since the advent of combination antiretroviral therapy (cART), several studies have described an increase in the incidence of Hodgkin lymphoma (HL). Risk of HIV-associated Hodgkin lymphoma during the first months after initiation of combination antiretroviral therapy From 12th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI) Bethesda, MD, USA. Background Since the advent of combination antiretroviral therapy (cART), several studies have described an increase in the incidence of Hodgkin lymphoma (HL).
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