Risk of bowel obstruction in patients undergoing neoadjuvant chemotherapy for high-risk colon cancer: A nested Case-control matched analysis of an international, multi-centre, randomised controlled trial (FOxTROT)

Abstract

Background: Implementation of neoadjuvant chemotherapy (NAC) for colon cancer may increase patient’s risk of bowel obstruction. This study aims to inform patient selection for NAC using features identifiable before treatment initiation.