Risk factors related to failure of internal fixation for intertrochanteric fracture in Chinese patients: a meta analysis and review

Abstract

Objective To evaluate the risk factors related to the failure of internal fixation for intertrochanteric fracture in Chinese patients. Methods A comprehensive Meta analysis of the clinical research from January 2005 to August 2016 on the failure of internal fixation for intertrochanteric fracture in Chinese patients was conducted after Pubmed, CNKI, Wanfang Data, et al., had been searched. Revman5.0 was used to perform the heterogeneity test and calculate the OR value and 95%CI after quality assessment and retrieval of the qualified data. Results Included for this analysis were 23 studies involving 4,031 pa-tients of whom 588 failed. The factors related to the failure of internal fixation for intertrochanteric fracture included patient age [OR=0.51, 95%CI (0.30, 0.90), P 0.05], injury cause [OR=1.68, 95%CI (0.66, 4.25), P >0.05] or type of internal fixation [OR=0.37, 95%CI (0.06, 2.14), P >0.05]. Conclusions High age, concomitant osteoporosis, complicated fracture pattern, unsatisfactory fracture reduc-tion, TAD≥25 mm, time for full weight bearing < 6 weeks, and concomitant internal diseases may be the risk factors closely related to the failure of internal fixation for intertrochanteric fracture in Chinese patients. There has been no sufficient evidence to show that gender, injury cause or type of internal fixation may be associated with the failed internal fixation for intertrochanteric fracture. Key words: Hip fractures; Fracture fixation, internal; Treatment failure; Meta-analysis