Abstract
BackgroundUreteral stenosis after percutaneous microwave ablation (MWA) of renal tumor is a rare but severe complication, and its risk factors are not apparent.PurposeThis study aimed to investigate the risk factors for stenosis of ureter after MWA treatment of the renal tumor that is a rare complication.Materials and MethodsData of 211 patients who underwent MWA for the treatment of renal tumor were retrospectively analyzed from September 2006 to August 2019. Demographic characteristics, clinical features, ablation parameters, and outcomes were analyzed to find out the potential risk factors of this complication. P < 0.05 is considered significant.ResultsSix of 211 patients developed ureter stenosis, and the rate of this complication is 2.84%. The median time of emergence of hydronephrosis was 226 (range, 3–390) days. Univariate analysis shows the distance between ureter and tumor (P = 0.225) or ablation zone (P = 0.089) is not related to this complication. Postoperative urine routine (red blood cell, P = 0.001; white blood cell, P = 0.035) and R.E.N.A.L. score (P < 0.001) is related to this complication. But after multivariate logistic analysis, only R.E.N.A.L. score (P = 0.004) is associated with this complication. The location and growth pattern of tumor and the energy of ablation were not related to this complication independently.ConclusionThe stenosis of the ureter after MWA of renal tumor is not associated with the tumor size, location, or the distance between the ureter and tumor and ablation site independently. But R.E.N.A.L. score is associated with ureter stenosis after MWA for the treatment of renal tumor, which combines the information of location, depth, and size of tumor. Preoperative evaluation of the tumor is necessary for avoiding ureter stenosis. Further studies should focus on these risk factors of this complication.
Highlights
The renal tumor is one of the fatal urological malignancies
Chen et al [17] had published a case report of ureteropelvic junction obliteration after RFA resulting in nephrectomy
Schmitz et al [18] have reported two cases of ureteropelvic junction stricture remote from the ablation site, which is similar to our study
Summary
The renal tumor is one of the fatal urological malignancies. The incidence of the renal tumor has been growing. Microwave ablation (MWA) for the renal tumor is a minimally invasive therapy, which can be performed under the guidance of ultrasound (US) or computed tomography (CT) during the operation or percutaneously directly. It has been proved in the previous study that MWA can achieve a similar effect and lower rate of complication compared with laparoscopic radical nephrectomy and open radical nephrectomy [6,7,8]. Ureteral stenosis after percutaneous microwave ablation (MWA) of renal tumor is a rare but severe complication, and its risk factors are not apparent.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
