Abstract
In this cross-sectional study, we investigated the baseline risk factors of diabetes mellitus (DM) in patients with undiagnosed DM (UDM). We utilized the Korean National Health and Nutrition Examination Survey (KNHANES) 2010–2017 data. Data regarding the participants’ demographic characteristics, health status, health determinants, healthcare accessibility, and laboratory tests were gathered to explore the differences between the DM, UDM, and without-DM groups. Among the 64,759 individuals who participated in the KNHANES 2010–2017, 32,611 individuals aged ≥20 years with fasting plasma glucose levels of <100 or ≥126 mg/dL were selected. The odds ratios (ORs) regarding family history of diabetes and the performance of national health and cancer screening tests were lower in the UDM group than in the DM group (adjusted OR: 0.54; 95% confidence interval (CI): 0.43, 0.66; adjusted OR: 0.74; 95% CI: 0.62, 0.89; adjusted OR: 0.71; 95% CI: 0.60, 0.85). The ORs of hypertension and obesity were higher in the UDM group than in the DM group (adjusted OR: 1.32; 95% CI: 1.06, 1.64; adjusted OR: 1.80; 95% CI: 1.37, 2.36, respectively). Patients with UDM were more likely to be exposed to DM-related risk factors than those with and without DM. Public health interventions to prevent UDM development are necessary.
Highlights
Diabetes mellitus (DM), a group of metabolic disorders characterized by high blood glucose levels, is a major global health issue
The distributions of overweightness and obesity were significantly different between the DM and undiagnosed DM (UDM) groups (OR: 2.12; 95% confidence interval (CI): 1.70, 2.65; odds ratios (ORs): 5.20; 95% CI: 4.34, 6.24, respectively); the magnitude of the ORs was larger than that of those observed in the DM group (OR: 1.67; 95% CI: 1.49, 1.88; OR: 2.73; 95% CI: 2.47, 3.02, respectively)
The ORs of hypertension and obesity were higher in the UDM group than in the DM group
Summary
Diabetes mellitus (DM), a group of metabolic disorders characterized by high blood glucose levels, is a major global health issue. 451 million people worldwide were estimated to have diabetes in 2017, and this value is expected to increase to 693 million by 2045 [1]. The global economic burden of DM has been estimated to substantially increase by 2030 [2]. In Korea, the estimated age-standardized prevalence rates of diabetes for men and women during 2013–2015 were 12.9% and 9.3%, respectively, showing significant increases from the values observed in 2005 [3]. Has the prevalence increased, and, approximately half of all diabetes cases, both worldwide and in Korea, remain undiagnosed [1,3,4]. Understanding undiagnosed DM (UDM) is critical to mitigating the substantial growth of the DM burden. People with DM are at a high risk of developing several life-threatening
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
