Abstract

PurposePostoperative pancreatic fistula (POPF) is one of the major complications in patients who undergo distal pancreatectomy (DP). Recently, dividing the pancreas by stapler is a commonly performed technique, however, POPF still occurs. Therefore, the purpose of this study was to investigate the risk factors for POPF after DP using a triple-row stapler.MethodsA total of 75 patients underwent DP using a triple-row stapler (Endo GIA™ Reloads with Tri-Staple™ Technology 60 mm; COVIDIEN, North Haven, CT, USA) at Yamanashi University from December 2012 to December 2016. The clinical risk factors for POPF after DP using a triple-row stapler were identified based on univariate and multivariate analyses.ResultsClinical POPF (ISGPF Grade B and C) was seen in 7 of 75 patients (9.3%). The body mass index (BMI) was significantly higher in the patients with POPF (26.8 ± 0.5 kg/m2) compared with the patients without POPF (21.4 ± 0.4 kg/m2; a cut-off value; 25.7 kg/m2). In addition, the patients with POPF were significantly younger than the patients without POPF (56.4 ± 5.6 vs 67.0 ± 1.5; a cut-off value was 57.0 years old).ConclusionsBMI and age were found to be significant risk factors for POPF after DP using a triple-row stapler.

Highlights

  • Perioperative management and operative techniques in pancreatic surgery have improved, post-operative pancreatic fistula (POPF) remains the most common complication after distal pancreatectomy (DP), occurring in from 5 to 32% of all cases [1,2,3,4,5,6] based on the International Study Group of Pancreatic Fistula (ISGPF) criteria [7]

  • Sex [8, 23], age [4, 24, 25], body mass index (BMI) [5, 8, 23, 25], diabetes mellitus [12, 25], the cartridge size [26], pancreatic thickness [1, 2, 4, 23, 25], chronic pancreatitis [27], extended lymphadenectomy [24], additional organ resection [8], and duration of operation [9, 12, 28] were described as risk factors

  • Since the risk factors for POPF after DP using a triple-row stapler have not yet been elucidated, the risk factors for POPF Grade B/C were determined in this study

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Summary

Introduction

Perioperative management and operative techniques in pancreatic surgery have improved, post-operative pancreatic fistula (POPF) remains the most common complication after distal pancreatectomy (DP), occurring in from 5 to 32% of all cases [1,2,3,4,5,6] based on the International Study Group of Pancreatic Fistula (ISGPF) criteria [7]. The superiority of stapler closure is not clear compared to the other techniques [3, 8, 12], the simple and easy stapler closure method is recently becoming one of the commonly performed techniques. This technique can close both the main pancreatic duct and the branch pancreatic duct at the same time. The purpose of this study was to investigate the risk factors for POPF after DP using a triple-row stapler

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