Risk factors of mortality in peritoneal dialysis patients

Abstract

Objective To explore the risk factors affecting the death of peritoneal dialysis patients. Methods The clinical data of 275 patients with peritoneal dialysis who place a peritoneal catheter in the Department of Nephrology, First Affiliated Hospital of Guangxi Medical University and had regular peritoneal dialysis for more than 3 months from January 1, 2005 to December 31, 2015 were retrospectively analyzed.Sixty patients died in the observation group, and 215 patients who continued regular peritoneal dialysis were in the control group.Univariate analysis and two-class logistic regression analysis were used to analyze risk factors for death. Results The composition ratio of the primary disease to diabetic nephropathy in the death group and the control group was 15.0% (9/60) and 5.6% (12/215), respectively, the average age of patients entering peritoneal dialysis was (50.6±14.3) years old and (45.7±13.2) years old, respectively(t=-2.518), glomerular filtration rates were 6.0(4.5, 9.4) and 5.1(4.2, 6.6), respectively, blood potassium is (4.2±0.7) mmol/L and (4.5±0.7) mmol/L, respectively, serum creatinine was 721.0 (585.0, 891.3) μmol/L and 847 (723.3, 1 033.3) μmol/L, respectively, there were significant differences between the two groups (t=2.14, all P<0.05). Logistic regression analysis indicated that the primary disease was diabetic nephropathy, and the age of admission to peritoneal dialysis, glomerular filtration rate, blood uric acid are risk factors for death in peritoneal dialysis patients. Conclusion Diabetic nephropathy, age, glomerular filtration rate, and blood uric acid level are independent risk factors for death in peritoneal dialysis patients. Key words: Peritoneal dialysis; Glomerular filtration rate; Risk factors