Abstract
Background: External ventricular drainage (EVD) is common after brain surgery. However, the incidence of EVD-related infection (ERI) is still relatively high and can increase morbidity and mortality.Objective: The objective of this study was to analyze ERI factors in pediatric population post-brain tumor surgery.Methods: From January 2016 to December 2017, 147 patients <18 years old underwent tumor removal at Beijing Tiantan Hospital and had postoperative EVD. We recorded basic demographic data as well as several risk factors. We then analyzed whether these factors were related to ERI.Results: Patients with a preoperative ventriculo-peritoneal (V-P) shunt, those with longer operation time, those who received blood transfusion, those with more frequent cerebrospinal fluid (CSF) sampling, and those with longer indwelling time of EVD had higher risks of infection (p < 0.05). Logistic regression analysis confirmed that a preoperative V-P shunt, operative duration, intraoperative blood transfusion, frequency of CSF sampling, and EVD duration were correlated with postoperative ERI (p < 0.05).Conclusion: EVD should be removed as soon as possible and any unnecessary procedures should be avoided to reduce the infection rate. However, prophylactic treatment should be given in case patients do not meet the indication for EVD removal.
Highlights
External ventricular drainage (EVD) is a common practice after brain tumor surgery since it helps monitor intracranial pressure and drain the residual blood [1,2,3,4]
The latest period of infection occurred on the 10th day after EVD placement with an incidence of 4.35%
There were 18 patients who had EVD placement for longer than 10 days; no infections were found in these patients (Figure 2)
Summary
External ventricular drainage (EVD) is a common practice after brain tumor surgery since it helps monitor intracranial pressure and drain the residual blood [1,2,3,4]. Risk Factors of EVD-Related Infections to multiple surgeries [7, 8]. There are few reports regarding intracranial infection in children with EVD, especially after brain tumor surgery. The purpose of this study was to investigate and analyze several risk factors of ERI in post-brain tumor surgery to elucidate the best treatment strategy to achieve a good prognosis. External ventricular drainage (EVD) is common after brain surgery. The incidence of EVD-related infection (ERI) is still relatively high and can increase morbidity and mortality
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