Risk factors of community-associated infections in Chinese patients with diabetes: A meta-analysis.

Abstract

ObjectiveTo identify the common sites and risk factors of community-associated infections in Chinese patients with diabetes.Materials and MethodsThe Wanfang, CNKI, PUBMED and VIP databases restricting to Chinese patients with diabetes were queried without restriction to time period. Randomized controlled trials (RCTs) on the risk factors of community-associated infections in Chinese patients with diabetes were considered. Polled odd ratios (OR) and 95% confidence intervals (95% CI) were used for each factor in fixed or random-effect meta-analyses.ResultsTwelve studies were identified that investigated seven risk factors of community-associated infections in Chinese patients with diabetes. The average infection incidence was 39.55%. The respiratory tract and urology tract were the predilection sites. Meta-analysis results are as follows: Diabetic patients with chronic complications (OR: 1.63; 95% CI 1.45–1.82), advanced age (OR: 1.30; 95% CI 1.19–1.42), longer duration (OR: 1.47; 95% CI 1.35–1.61) or ketoacidosis (OR: 1.37; 95% CI 1.13–1.66) were more prone to suffer from infections. Those with better glycemic control (OR: 0.68; 95% CI 0.61–0.76) or males (OR: 0.69; 95% CI 0.64–0.75) were less prone to suffer from infections.ConclusionChinese patients with diabetes had a high incidence of community-associated infections. We should highlight the risk factors that might provide a reference for the same.