Abstract
RISK FACTORS OF CHOLELITHIASIS RELAPSE AFTER LITHOTRIPSY AND DURING PROPHILACTIC TREATMENT WITH BILE ACIDS: PRELIMINARY RESULTS OF TWO-YEARS FOLLOW-UP STUDY V. Isakov l, T. Petukhova, M. Brekhova, A. Mironov, I. Ivanikov Central Hospital Medical Centre of RF President Adm. Dep., Department of Gastroenterology, Moscow Russia. 1MONIKI, Moscow, Russia. The aim: To establish risk factors of cholelithiasis relapse after lithotripsy and during long-term prophylactic therapy with bile acids. 205 patients (Male/Female=55/150; mean age 45,6 yrs) after successful gallbladder lithotripsy were enrolled for the prophylactic therapy with ursodeoxycholic acid (dosage 10mg/kg per day) for 24 months with ultrasound control every 3 months. During the follow-up period 128 (62,4%) patients relapsed. Multivariate analysis revealed that age (Table), 20% increase of body mass index, 10% increase of blood cholesterol indelmndently increase risk o f relapse of cholelithiasis. Age group Patients in remission after 2 years (%) p
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