Risk factors of atherogenic index of plasma in elderly male hypertensive patients

Abstract

To investigate the risk factors of atherogenic index of plasma (AIP) in elderly male hypertensive patients. According to the cutoff point of AIP at 0.06, 384 elderly male hypertensive patients with AIP≥0.06 were enrolled as atherogenic phenotype group(A group) while 352 age and blood pressure matched male hypertensive patients with AIP<0.06 were enrolled as non-atherogenic phenotype group (NA group). Clinical biochemistry data and physical examination indexes were compared between the two groups. Parametric test showed that uric acid (UA), fasting blood-glucose (FBG), body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR) in group A were higher than those in group NA (all P<0.01). Binary logistic regression analysis revealed that WC, UA, FBG were independent risk factors of AIP (all P<0.01). These results indicate that elderly male hypertensive patients should regularly monitor and control their waist circumference, uric acid and fasting blood glucose levels to better control AIP and the risk of developing atherosclerosis. Before conducting relevant blood and imaging examinations, waist circumference can serve as a preliminary screening index for atherosclerosis in this population, evaluating their AIP level and atherosclerosis risk. Key words: Hypertension; Atherosclerosis; Risk factors