Risk factors for the incursion, spread and persistence of the foot and mouth disease virus in Eastern Rwanda

Jean Claude Udahemuka,Joshua Orungo Onono,George Ogello Obiero,Massimo Paone,Phiyani Justice Lebea,Gabriel Oluga Aboge

doi:10.1186/s12917-020-02610-1

Abstract

BackgroundIdentification of risk factors is crucial in Foot-and-mouth disease (FMD) control especially in endemic countries. In Rwanda, almost all outbreaks of Foot-and-Mouth Disease Virus (FMDV) have started in Eastern Rwanda. Identifying the risk factors in this area will support government control efforts. This study was carried out to identify and map different risk factors for the incursion, spread and persistence of FMDV in Eastern Rwanda. Questionnaires were administered during farm visits to establish risk factors for FMD outbreaks. Descriptive statistical measures were determined and odds ratios were calculated to determine the effects of risk factors on the occurrence of FMD. Quantum Geographic Information System (QGIS) was used to produce thematic maps on the proportion of putative risk factors for FMD per village.ResultsBased on farmers’ perceptions, 85.31% (with p < 0.01) experienced more outbreaks during the major dry season, a finding consistent with other reports in other parts of the world. Univariate analysis revealed that mixed farming (OR = 1.501, p = 0.163, CI = 95%), and natural breeding method (OR = 1.626; p = 0.21, CI = 95%) were associated with the occurrence of FMD indicating that the two risk factors could be responsible for FMD outbreaks in the farms. The occurrence of FMD in the farms was found to be significantly associated with lack of vaccination of calves younger than 12 months in herds (OR = 0.707; p = 0.046, CI = 95%).ConclusionsThis is the first study to describe risk factors for persistence of FMDV in livestock systems in Rwanda. However, further studies are required to understand the role of transboundary animal movements and genotypic profiles of circulating FMDV in farming systems in Rwanda.

Highlights

Identification of risk factors is crucial in Foot-and-mouth disease (FMD) control especially in endemic countries
There was no active outbreak of FMD in the visited farms during the interviewing period, the last outbreaks had occurred between May 2017 and February 2018 and were caused by serotypes Southern African Territories (SAT) 2 [7]
The samples were shipped to the Virology laboratory of the Rwanda Agriculture Board to confirm the outbreak by Enzyme-Linked Immunosorbent Assay (ELISA) and Polymerase Chain Reaction (PCR)

Summary

Introduction

Identification of risk factors is crucial in Foot-and-mouth disease (FMD) control especially in endemic countries. In Rwanda, almost all outbreaks of Foot-and-Mouth Disease Virus (FMDV) have started in Eastern Rwanda. FMD affects cloven-hoofed animals including domestic and wild animals [2]. The East African region is considered to have the most complicated situation with regard to the control of FMD. This is due to interactions between domestic and wild animals susceptible to FMD, uncontrolled transboundary animal movements and high genetic diversity of FMDV in the region [3]. The Akagera National Park (ANP) is home to many FMD susceptible wild animals, which are at of risk of interacting with livestock in farms adjacent to ANP. The other outbreaks of FMD involving serotypes A and SAT1 occurred in 2008, 2009, 2010 [9] and again serotype SAT1 in 2012–2013 [10]

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Results

Conclusion