Risk factors for secondary MODS in elderly coma patients due to cerebral hemorrhage

Abstract

Objective To analyze the risk factors for secondary multiple organ dysfunction syndrome(MODS) in elderly coma patients due to cerebral hemorrhage, in order to provide clinical evidence for the effective prevention and treatment of MODS in elderly coma patients due to cerebral hemorrhage. Methods Seventy-eight senile cerebral hemorrhage coma patients were selected, and were divided into MODS group and non MODS group during hospitalization, the quantitative parameters were compared between the two groups, and the independent risk factors of MODS were analyzed by Logistic regression analysis. Results There were 31 patients (18.25%) with MODS among the 78 patients; The scores of IL-1, IL-10, CRP, APACHE-Ⅱ, blood glucose and cerebral hemorrhage in MODS group were significantly higher than those of patients without MODS group, GCS score and serum albumin were significantly lower than those of patients without MODS group, the differences were significant (P<0.05); Logistic regression analysis showed that blood glucose, APACHE Ⅱ score, cerebral hemorrhage volume, serum albumin, IL-6 and IL-10 were the independent risk factors for MODS in elderly patients with cerebral hemorrhage (P<0.05). Conclusions Inflammatory response, blood glucose level, cerebral hemorrhage volume, APACHE Ⅱ score, nutritional status are closely correlated with the elderly cerebral hemorrhage coma patients, improve the patient's general condition, effectively control blood sugar levels, and reduce the occurrence of MODS is needed. Key words: Cerebral hemorrhage; Coma; Multiple organ dysfunction syndrome; Risk factors; Analysis