Risk factors for post-surgical pulmonary complications in patients after esophagectomy for cancer:a multivariate Logistic analysis

Abstract

Objective To identify risk factors for post-surgical pulmonary complications in patients with mechanical ventilation for respiratory failure and pneumonia after esphagectomy in order to guide the development of individualized treatment-plan for high risk patients.Methods Clinical data from 82 patients received esophagectomy for cancer during May 2008 to June 2010 were analyzed retrospectively using Logistic regression for risk factors associated with the development of post-surgical pulmonary complication Results Post-surgical pulmonary complications was found in 12 0ut of the 82 patients studied,and it was the primarily death cause for one of them.Multivariate Logistic analysis identified advanced age [odds ratio (OR) ～ 1.28,95% confidence interval (95%CI) 1.05 - 1.62,P= 0.03l,impaired pulmonary function (forced expiratory volume in one second (FEVi) OR = 1.20,95%CI l.08 - 1.39,P = 0.02) and longer operation duration (OR = 1.68,95%CI l.37 - 2.11,P= 0.003) as risk factors.Conclusion Advanced age and impaired lung function may be significant risk factors for pulmonary complications after esophagectomy.It is helpful to evaluate the risk of such complications by referring to these indexes before the surgery,and design individualized treatment-plan for patients at high risk. Key words: Esophagectomy; Pulmonary complication; Risk factors