Risk Factors for Peritoneal Dialysis-Associated Peritonitis Due to Home-Based Operation Management: A Retrospective Cohort Study.

Abstract

This study aimed to explore the risk factors related to home-based operation management leading to the occurrence of peritoneal dialysis-associated peritonitis (PDAP). An observational research was conducted. A retrospective analysis was conducted among patients with maintenance peritoneal dialysis (PD) between 1 January 2019 and 31 December 2022. The patients were grouped according to the occurrence of PDAP. General characteristics and home operational data were collected and logistic regression analysis was performed to identify independent risk factors for PDAP associated with home operations. This study complied with the Appendix S1. Of 458 PD patients included in this study, 82 were in the peritonitis group. Their average age was 53.34 ± 13.62 years, and the average dialysis vintage was 35.57 ± 32.74 months, with males accounting for 54.6%. Multivariate logistic regression analysis revealed that age; primary disease, such as diabetes mellitus; dialysis vintage; improper storage of dialysis fluid; failure to verify the quality of protective-caps with povidone-iodine; and improper handwashing were risk factors of PDAP. Daytime ambulatory PD mode was significantly negatively associated with PDAP. Improper storage of dialysis fluid, failure to check the quality of protective-caps and improper handwashing at home are independent risk factors for PDAP caused by home-based operation management. Nurses should strengthen relevant training or retraining to address this. These findings serve to highlight the key areas for training in PD management and aim to empower patients to effectively conduct self-management practices. We appreciate the patient's understanding and support.