Abstract
The reason of the biological stability loss of mini-implants is still a matter of discussion between dentistry professionals. The main objective of this systematic literature review and meta-analysis was to analyze the risk factors that prejudice this loss. A search was made in the electronic databases Pubmed, Scopus, Embase and Cochrane, in addition a manual search was made too in Grey Literature (Opengrey). No limits were set on the year of publication or language. The inclusion criteria were: studies in humans treated with fixed appliances with mini-implants, where the risk factors for secondary stability were evaluated for a minimum of 8 weeks. After eliminating duplicate studies and assessing which ones achieve the inclusion criteria, a total of 26 studies were selected for the qualitative synthesis, 18 of them were included in the quantitative synthesis. Common risk variables were compared in all of them. Analyzing the forest and funnel plots, statistically significant differences were obtained only for location, the upper maxilla having lower risk than the mandible with an odds ratio of 0.56 and confidence interval of 0.39 to 0.80. Prospective studies under controlled conditions should be required in order to obtain a correct assessment of the variables analyzed.
Highlights
After reading the titles and abstracts of the selected papers, 731 articles were discarded leaving 60 studies for thorough assessment. Full texts of these 60 studies were revised and 34 articles were eliminated as these were literature reviews or meta-analyses or because they failed to answer the research question or did not meet inclusion criteria (Table 1)
Odds ratios and confidence intervals showed that none of these variables reached statistical significance
With regard to placement on the left side or right side, or in anterior or posterior regions, statistically significant relations were found for both variables
Summary
RECORDS EXCLUDED Männchen et al, 2008 Ji et al, 2008 Tsoudis et al, 2008 Reynders et al, 2009 Antoszewska et al, 2009 Schätzle et al, 2009 Schätzle et al, 2010 Kim et al, 2010 Papadopoulus et al, 2011 Min et al, 2012 Consolaro et al, 2014 Kuroda et al, 2014 Rodriguez et al, 2014 Dalesandri et al, 2014 Romano et al, 2015 Uribe et al, 2015 Cornelis et al, 2015 Papadopoulus et al, 2015 Sarul et al, 2015 Lin et al, 2015 Liu et al, 2016 Kim et al, 2016 Leo et al, 2016 Hong et al, 2016 Yi et al, 2016 Afrashtehfer et al, 2016 Yi et al, 2017 Alharbi et al, 2018 Mohammed et al, 2018 Lyczek et al, 2019 Azeem et al, 2019 Azeem et al, 2019 Kakali et al, 2019 Ichsnoke et al, 20
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