Risk factors for myocardial injury at admission of 325 patients with coronavirus disease 2019 in Shanghai, China

Abstract

ObjectiveMyocardial injury leads to higher mortality in COVID‐19, but the causes and risk factors are variable. We evaluated the potential risk factors for myocardial injury in COVID‐19 patients to improve treatment strategies and reduce mortality.MethodsThis retrospective analysis enrolled 325 COVID‐19 patients in Shanghai, China.ResultsThe median age in our cohort was 51 [range 15‐88] years, 26 (8%) were critically ill, and 177 patients (19.7%) had myocardial injury. The myocardial injury group comprised older, more critically ill patients with hypertension, other comorbidities, history of angiotensin‐converting enzyme inhibitor/angiotensin receptor blocker use, lower peripheral blood lymphocyte count and higher D‐dimer levels. Binary logistic regression analysis identified only age was an independent risk factor for myocardial injury (odds ratio 1.019; 95% confidence interval 1.003‐1.036; age increase by 1 year = myocardial injury risk increase by 1.9%).ConclusionsOlder age was associated with a higher incidence of myocardial injury for COVID‐19 patients.