Abstract
Factors that predict recurrence of febrile seizures (FS) were determined in a prospective study of 260 children age 3 months to 6 years followed for a median of 4.3 years after the first FS at Ippokratio Hospital, Aristotle University of Thessaloniki, Greece.
Highlights
Multiple recurrences were correlated with low temperature elevation (
In a study of 13 children with acute encephalopathy following prolonged febrile seizures compared to 23 without encephalopathy, in Yamaguchi University and other centers in Japan, serum IL-6, IL-10, TNFR1 and CSF IL-6 levels were significantly higher in subjects with encephalopathy compared to controls without encephalopathy
Literature regarding pertussis vaccination and risk of encephalopathy and/or epilepsy is reviewed by researchers from UCL Institute of Neurology, London, UK, and North Illinois University, DeKalb, IL, USA
Summary
Factors that predict recurrence of febrile seizures (FS) were determined in a prospective study of 260 children age 3 months to 6 years followed for a median of 4.3 years after the first FS at Ippokratio Hospital, Aristotle University of Thessaloniki, Greece. Low age at onset and positive family history of FS, especially maternal, were strong predictors of recurrence. Other risk factors included abnormal perinatal history with low Apgar score and NICU care for >3 days, low temperature (38.9C or below) and short (
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