Abstract

BackgroundTo investigate the risk factors for early seizure after revascularization in patients with moyamoya disease (MMD).MethodsA total of 298 patients with MMD diagnosed in our hospital from 2015 to 2018 were analyzed retrospectively. We summarized the characteristics of seizure after revascularization in patients with MMD and analyzed the predictors of early postoperative seizure.ResultsWe identified 15 patients with MMD who developed seizures within 1 week after revascularization. According to logistic regression analysis, age (OR: 1.04, 95% CI 0.998–1.086; P = 0.060) and infarct side (OR: 1.92, 95% CI 0.856–4.290; P = 0.113) were not significantly associated with incident early seizure. Postoperative infarction (OR: 12.89, 95% CI 4.198–39.525; P = 0.000) and preoperative cerebral infarction (OR: 4.08, 95% CI 1.267–13.119; P = 0.018) were confirmed as risk factors for early seizure.ConclusionsWe believe that a history of preoperative infarction and new infarction are independent risk factors of early seizure in patients with MMD after revascularization.

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