Abstract

To investigate the risk factors associated with candida infection of the genital tract in the tropics. We performed questionnaire survey and experiments at the Hainan branch of General Hospital of People's Liberation Army, Hainan General Hospital and Sanya Maternity and Child Health Care Hospital in 2013. Controls were without Candida infection of genital tract, and cases had from Candida infection. We recruited 689 cases and 652 controls. The average age of cases with Candida infection of the genital tract was higher than that of controls. In the multivariate modeling, marriage (adjusted odds ratio: 2.49, 95% confidential interval: 1.09-5.67) and vaginal lavage (adjusted odds ratio: 4.41, 95% confidential interval: 1.13-5.14) were significantly associated with Candida infection of genital tract in tropics. Candida infection was related with age. Marriage and Vaginal lavage were significant risk factors. Attention should be paid to health education for the prevention of these infections.

Highlights

  • Candidal vaginitis represents one of the most common gynecological disorders[1]

  • Almost 75% women will have a candidal vulvovaginitis during their life span, and nearly half of them will suffer from a second event[5]

  • 689 patients were infected by Candida spp. 382 infected patients and 263 controls responded to a simplified questionnaire survey

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Summary

Introduction

Candidal vaginitis represents one of the most common gynecological disorders[1]. Common risk factors for Candida infection are recent antibiotic use, pregnancy, diabetes mellitus, oral-contraceptives and inadequate therapy[2]. Isolation of Candida (species) spp. from samples of vaginal exudates is a very frequent thing. It is widely perceived that the incidence of Candida infection is rising. This motivated the study to search for potential risk factors and to potentially prevent Candida infection. Identification of risk factors is a very important way in the prevention of diseases. The objective of this study was to determine the risk factors for Candida infection of genital tract in the tropics and provide a basis for disease infection

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