Risk factors for and relationship between bacterial vaginosis and cervicitis in a high risk population for cervicitis in Southern Iran.

Abstract

In 1990, a study of the reproductive habits and cervical pathology in women of the Qashgha'i nomadic tribe, resulted in a high prevalence of cervicitis. This led us to explore the likely infectious agents responsible for a such high prevalence; to assess the difference in cervicitis rates between nomadic and non-nomadic populations in the same area; and to determine the risk factors for and the relationship between cervicitis and bacterial vaginosis (BV). In 1996-1997 a study was carried out of 839 married women of the Qashgha'i, 274 of the Lor nomadic tribes, and 388 non-nomadic urban women. A gynaecological examination, Pap smear and vaginal secretion for assessing BV by gram staining were performed. Data was analysed by logistic regression. Backward stepwise regression was used to assess multivariable effects on risk of cervicitis. The prevalence of cervicitis was 88% in the Qashgha'i, 85% in the Lor and 71% in the urban population. In the multivariate backward stepwise regression analysis for predictors of cervicitis in the Qashgha'i, significant factors were decreased association with those over 40 (p < 0.004) and postpartum bleeding. In the Lor tribe the predictors were an increased risk after more than four pregnancies (p < 0.01) and the use of contraception. Among the urban population, the risk of cervicitis was increased with the use of oral contraceptive previously (p < 0.03) or currently (p < 0.01). BV was strongly associated with cervicitis, with a relatively high attributable risk. Both sexual and childbirth exposures may be associated with cervicitis in these populations.