Abstract
ObjectivesPostoperative complications increase the workload of nursing staff as well as the financial and mental distress suffered by patients. The objective of this study is to identify clinical factors associated with postoperative complications after liver cancer resection surgery.MethodsData from liver cancer resections occurring between January 1st, 2019 to December 31st, 2019 was collected from the Department of Liver Surgery in West China Hospital of Sichuan University. The Kruskal–Wallis test and logistic regression were used to perform single-factor analysis. Stepwise logistic regression was used for multivariate analysis. Models were established using R 4.0.2 software.ResultsBased on data collected from 593 cases, the single-factor analysis determined that there were statistically significant differences in BMI, incision type, incision length, duration, incision range, and bleeding between cases that experienced complications within 30 days after surgery and those did not. Stepwise logistic regression models based on Kruskal–Wallis test and single-factor logistic regression determined that BMI, incision length, and duration were the primary factors causing complications after liver resection. The adjust OR of overweight patients and patients with obesity (stage 1) compared to low weight patients were 0.12 (95% CI:0.02–0.72) with p = 0.043 and 0.18 (95% CI:0.03–1.00) with p = 0.04, respectively. An increase of 1 cm in incision length increased the relative risk by 13%, while an increase of 10 min in surgical duration increased the relative risk by 15%.ConclusionsThe risk of postoperative complications after liver resection can be significantly reduced by controlling factors such as bleeding, incision length, and duration of the surgery.
Highlights
Liver cancer has the sixth-highest morbidity and the fourth highest mortality in the world
Our research indicates that high blood loss grade 2 patients were 3.43 times more likely to suffer complications after liver resection surgery than low blood loss grade 1 groups, (bleeding > 500 ml, adjusted OR: 3.56, p = 0.00036)
Postoperative complications after liver cancer resection surgery have attracted the attention of many researchers, and many studies have found out risk factors (11,14–16)
Summary
Liver cancer has the sixth-highest morbidity and the fourth highest mortality in the world. It has the fourthhighest morbidity and mortality in China [1]. The National Cancer Center collected evidence and conducted a systematic evaluation of the economic burden of liver cancer in China between 1996 to 2015, it was concluded that the average direct medical costs incurred in hospitals of cases between 1996 to 2013 gradually increased, with a median of 1804.3 US dollars (541.45–10,916.7 US $) [5].The indirect economic burden, based on the human capital method, includes the lost working hours and early death of liver cancer patients as well as the lost working hours of caretakers. Through statistical analysis of the second-hand data, it can be concluded that suffering from liver cancer affects family income severely and has high indirect costs. [6, 7]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
