Abstract
No studies have explored the risk factors for paraurethral duct dilatation following paraurethral duct infection by Neisseria gonorrhoeae in men undergoing ceftriaxone therapy. The present study was performed to explore the risk factors for paraurethral duct dilatation following paraurethral duct infection by N. gonorrhoeae in men undergoing ceftriaxone therapy and thus guide clinical interventions. We compared the demographic, behavioral, and clinical data of men with paraurethral duct infection by N. gonorrhoeae with and without dilatation of the paraurethral duct. Univariate analysis showed significant differences in age, disease course of the infected paraurethral duct, Chlamydia trachomatis infection in the paraurethral duct, and a history of paraurethral duct infection by N. gonorrhoeae between the patient and control groups (P<0.05). Multivariate logistic regression analysis showed consistent results (P<0.05). This study that shows delayed treatment may be a major risk factor for paraurethral duct dilatation secondary to paraurethral duct infection by N. gonorrhoeae in men. Age, C. trachomatis infection in the paraurethral duct, and a history of paraurethral duct infection by N. gonorrhoeae are also risk factors. Thus, educating patients to undergo timely therapy and treating the C. trachomatis infection may be effective interventions.
Highlights
The paraurethral ducts in men are small, blind channels lined with columnar epithelium [1]
Infection of the paraurethral duct by N. gonorrhoeae is a localized complication in male patients with gonorrhea
7058 male patients with gonorrhea that was confirmed both clinically and by laboratory test results were treated in our department from October 1997 to May 2015, and 106 (1.50%) of these patients had accompanying paraurethral duct infection by N. gonorrhoeae
Summary
The paraurethral ducts in men are small, blind channels lined with columnar epithelium [1]. These ducts run parallel to the terminal part of the urethra for varying distances and open near or within the lips of the external meatus [2]. The paraurethral ducts appear to be embryological remnants and are not visible to the naked eye [3]. Neisseria gonorrhoeae can infect the paraurethral duct. Such infection clinically manifests as an erythematous swelling of the external.
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