Abstract
Objective To investigate the situation of the mother-to-child transmission of HIV in Henan province so as to explore the risk and protective factors. Methods The data regarding HIV-infected pregnant women and their infants from 2002 to 2013 were collected from (national notifiable disease reporting system), including PITC, perinatal health service, ART and follow-up examination for infants. Univariate and multivariate logistic regression model were used to explore the influencing factors. Results A total of 1 384 infants survived to 18 months old, including a 60 HIV-positive infants and 1 324 HIV-negative infants. The MTCT rate was 4.34% which did not show significant decreasing from 2002 to 2013 (x2=2.82, P=0.093). VCT in early pregnancy (0R=0.22, 95% C.I. 0.06~0.77), standardized ARV regimen in early pregnancy (0R=0.46, 95% C.I. 0.21~0.91), artificial feeding (0R=0.08, 95% C.I. 0.02~0.30) may be the main protective factors; episiotomies on delivery (0R=3.17, 95% C.I. 1.37~7.36) may be the risk factors. Conclusions The MTCT rate is higher in Henan province, and the targeted interventions of MTCT should be further improved. Key words: AIDS; Mother-to-child transmission; Infant; Influencing factors
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