Abstract

We conducted a nationwide population-based cohort study to identify the risk factors associated with failure of total ankle arthroplasty (TAA). We included 2,914 subjects who underwent primary TAA between January 1, 2010, and December 31, 2016, utilizing the database of the Korean National Health Insurance Service. Failure of TAA was defined as revision TAA or arthrodesis procedures. An increased risk of TAA failure was observed in the < 65 age group versus the ≥ 75 age group [adjusted hazard ratios (aHR) 2.273, 95% confidence interval (CI) 1.223–4.226 in the 60–64 age group; aHR 2.697, 95% CI 1.405–5.178 in the 55–59 age group; aHR 2.281, 95% CI 1.145–4.543 in the 50–54 age group; aHR 2.851, 95% CI 1.311–6.203 in the < 50 age group]. Conversely, the ≥ 65 age group displayed no increase in the risk of TAA failure. The risk of TAA failure was increased in the severely obese group with body mass index (BMI) of ≥ 30 kg/m2 versus the normal BMI group (aHR 1.632; 95% CI 1.036–2.570). This population-based longitudinal study demonstrated that age < 65 years and BMI of ≥ 30 kg/m2 were associated with increased risk of TAA failure.

Highlights

  • We conducted a nationwide population-based cohort study to identify the risk factors associated with failure of total ankle arthroplasty (TAA)

  • We identified all primary TAAs performed in the country, that were defined by the claim codes N2075 and N2079, between January 1, 2010 and December 31, 2016

  • Even though the popularity of TAA is growing for the treatment of end-stage ankle arthritis along with advances in implant design and surgical techniques, the complication and reoperation rates after primary TAA still remain high compared with those for ­AA3,29

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Summary

Introduction

We conducted a nationwide population-based cohort study to identify the risk factors associated with failure of total ankle arthroplasty (TAA). The risk of TAA failure was increased in the severely obese group with body mass index (BMI) of ≥ 30 kg/m2 versus the normal BMI group (aHR 1.632; 95% CI 1.036– 2.570). This population-based longitudinal study demonstrated that age < 65 years and BMI of ≥ 30 kg/ m2 were associated with increased risk of TAA failure. Numerous studies have investigated the risk factors associated with failure of TAA, and the identified risk factors include age, body mass index (BMI), diabetes, rheumatoid arthritis, smoking, and preoperative ­deformity[5,18,19,20,21,22,23,24]. This study aimed to identify the risk factors associated with failure of TAA by utilizing the data derived from the entire South Korean population

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