Risk Factors and Long Term Outcome in Young Adults with Spontaneous Intracerebral Hemorrhage (P02.211)

Abstract

Objective: This study was performed to compare the risk factors, location of hemorrhage and long term outcome in spontaneous intracerebral (ICH) hemorrhage in young and elderly. Background Intracerebral hemorrhage accounts for about 15% of Cerebrovascular accident, and is one of the common cause of mortality and long term morbidity. Design/Methods: A total of 108 subjects of intracerebral hemorrhage from the stroke were analysed. The patients were divided into young ( 45yr). The associated risk factors, locations of hemorrhage and long-term were determined. Twenty six young adults of ICH Patients were followed up from 1 year and to 7 year and long term morbidity was estimated according to mRS in both the groups. Results: Hypertension was most common risk factor 88 (81.4%), DM in 23 (21.2%). 19 patients (17.6%) had both hypertension and DM. 32(29.6%) were smokers. Basal ganglia was the commonest site of hemorrhage in 53 cases (49%), Thalamus 29 (26.85%), lobar hemorrhage 12(11.11%), Brain stem 9 (8.3%), cerebellar 5 (4.6%) case. CT scan was the most common initial imaging. Young ICH accounted for 26 cases (24.07%). Among risk factors in the young vs elderly group, Hypertension was present in 19 (73%) vs 69 (84%), DM 9 (34.6%) vs 14 (20.3). Smoking in 5 (19.2%) vs 27(32.9%).Basal ganglia was the commonest site of hemorrhage in both groups 15 (57.7%) vs 38 (46.3%), followed by thalamus 6 (23%) vs 23 (28%), brainstem 3 (11.5%) vs 6 (7.3%).The average mRS at 1 year was comparable in both groups 1.16 (n-8) vs 1.12 (n-17), but subsequent scoring at 2 yr was 0.25 (n-4) vs 1.08 (n-12), at 3 yr 0.33(n-3) vs 0.83 (n-12). Conclusions: Hypertension was the single most common cause for Spontaneous ICH. Aggressive screening and timely management will be helpful to prevent ICH and disability in young adults. Disclosure: Dr. Mehndiratta has nothing to disclose. Dr. Chakravarty has nothing to disclose. Dr. Mehndiratta has nothing to disclose.