Abstract

Objective:The objective of this study was to find out the maternal risk factors and perinatal complications in small for gestational age (SGA) newborns.Methods:A total of 181 SGA cases and 1299 cases of appropriate for gestational age (AGA) with the same gestational age between January 2015 and December 2016 were enrolled in Linyi People’s Hospital, China. The risk factors were analyzed and the frequencies of perinatal complications were compared between the two groups.Results:The frequencies of maternal risk factors such as pregnancy-induced hypertension, abnormal placenta and twins in the SGA group were significantly higher than that in the AGA group (P<0.05). The incidence of hyperbilirubinemia and hypoglycemia in the perinatal period was also higher in the SGA newborns group (P<0.05), while there were no significant differences in the incidence of pneumonia, apnea, septicemia, intracranial hemorrhage, neonatal asphyxia, congenital malformations, hypoxic-ischemic encephalopathy, respiratory distress syndrome and necrotizing enterocolitis between the two groups.Conclusions:SGA can cause perinatal complications including neonatal hypoglycemia and hyperbilirubinemia. It is necessary to strengthen the perinatal monitoring and antenatal care to reduce SGA and the perinatal complications of SGA.

Highlights

  • Small for gestational age infant (SGA) was defined by the WHO in 1995 as the infant with birth weight below the 10th percentile of mean body weight of the infants of same gestational age and same gender.[1]

  • In 2001, the World SGA Development Conference announced that SGA refers to birth weight and/ or body length below averagely two standard deviations (≤-2s) of same gestational age, about the third percentile of body weight and/or body length of same gestational age.[2]

  • The frequencies of hypoglycemia (P

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Summary

Introduction

Small for gestational age infant (SGA) was defined by the WHO in 1995 as the infant with birth weight below the 10th percentile of mean body weight of the infants of same gestational age and same gender.[1] In 2001, the World SGA Development Conference announced that SGA refers to birth weight and/ or body length below averagely two standard deviations (≤-2s) of same gestational age, about the third percentile of body weight and/or body length of same gestational age.[2]. Pak J Med Sci September - October 2019 Vol 35 No 5 www.pjms.org.pk 1199 difficulties, language barriers and cognitive and behavioral defects[7,8,9], and even increasing the incidence of autism.[10] SGA is closely related to some important diseases in adulthood.[11] The prevalence of SGA births has been reported to be 8.6%–11.4% in several countries,[12] while in China, the overall prevalence of SGA is estimated to be 8%-13%.13

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