Risk factors and clinical manifestations of respiratory failure accompanied by gastrointestinal insufficiency in “early” full-term newborns

Abstract

The aim of the study is to identification of risk factors and features of the course of respiratory failure accompanied by gastrointestinal insufficiency in “early” full-term newborns s Methods. The study design is retrospective, controlled, non - randomized, single-center.. Inclusion criteria are newborns with a gestation period of 37 weeks. Exclusion criteria congenital malformations that require emergency surgical correction. 279 patients met the inclusion and exclusion criteria. 3 (1.1%) children were killed. 36 (12.9%) children developed severe respiratory failure. Statistical processing was carried out on the basis of the “BioStat”program. Results. Respiratory problems were realized mainly in newborns extracted by emergency caesarean section (OR = 1,2, χ2 = 5,12, p=0,04). The duration and severity of enteral insufficiency was associated with the degree of respiratory disorders Moreover, prevention with corticosteroids contributed to the use of less aggressive and respiratory support methods in these children. Conclusions. The most significant risk factor for the development of severe respiratory failure in “early” full-term patients is performing a caesarean section for emergency indications. Antenatal steroid prevention of respiratory failure in “early” full-term infants may help reduce the frequency of aggressive methods of artificial respiratory support. The severity of respiratory failure is also associated with gastrointestinal insufficiency.