Risk Factors Analysis Of Depression In Pediatric Acute Lymphoblastic Leukemia

Abstract

Objective: This study aims to analyze the risk factors that influence the degree of depression in pediatric ALL patients. Patients with ALL, especially children and adolescents, are faced with many psychological and social problems. One of the most common problems of emotional change is depression. It is still unknown what risk factors can affect the degree of depression in pediatric ALL patients. Methods: A cross-sectional analytical observational study was conductedch by collecting interview data and filling out the PHQ-9 questionnaire from pediatric ALL patients treated at Dr. Soetomo Surabaya in the period September 2020-March 2021. The patient's sociodemographic factors, parents' sociodemographic and the patient's clinical condition as a risk factors for the degree of depression were analyzed. The Chi-Square Test, Fischer's Exact Test, and multivariate logistic regression were undertaken. There were 40 samples pediatric ALL patients. Results: Most of the samples (34 patients, 85%) were grouped in the mild depression group (total PHQ score was 0-9). It was found in the results of the multivariate analysis that had been carried out from several variables analyzed, only comorbidities had p=0.007 (p<0.05), this showed a significant result. Conclusions: Patient's comorbidities were associated with the severity of depression in pediatric ALL patients.