Risk Factors Affecting the Severity of Full-Term Neonatal Retinal Hemorrhage

Zhang Yanli,Lin Yu,Zhao Qi,Guo Haike

doi:10.1155/2017/4231489

Zhang Yanli, Lin Yu + Show 2 more

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https://doi.org/10.1155/2017/4231489

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Abstract

Objective The purpose of this study was to explore the underlying clinical factors associated with the degree of retinal hemorrhage (RH) in full-term newborns. Methods A total of 3054 full-term infants were included in this study. Eye examinations were performed with RetCamIII within one week of birth for all infants. Maternal, obstetric, and neonatal parameters were compared between newborns with RH and controls. The RH group was divided into three sections (I, II, and III) based on the degree of RH. Results RH was observed in 1202 of 3054 infants (39.36%) in this study. The quantity and proportion of newborns in groups I, II, and III were 408 (13.36%), 610 (19.97%), and 184 (6.03%), respectively. Spontaneous vaginal delivery (SVD), prolonged duration of second stage of labor, advanced maternal age, and neonatal intracranial hemorrhage positively correlated with aggravation of the degree of RH in newborns. Conversely, cesarean section was protective against the incidence of RH. Conclusions SVD, prolonged duration of second stage of labor, advanced maternal age, and neonatal intracranial hemorrhage were potential risk factors for aggravation of the degree of RH in full-term infants. Accordingly, infants with these risk factors may require greater attention with respect to RH development.

Highlights

Neonatal retinal hemorrhage (RH) is a clinically common neonatal fundus condition occurring in newborns within one month of birth [1]
Neonatal RH does not affect the development of visual function, macular hemorrhage may lead to amblyopia due to the delayed absorption caused by bleeding [2]
RH is one of the most commonly seen ocular abnormalities in newborns, and it may have a serious impact on the visual function and quality of life of the affected child when it affects the macula

Summary

Introduction

Neonatal retinal hemorrhage (RH) is a clinically common neonatal fundus condition occurring in newborns within one month of birth [1]. Neonatal RH does not affect the development of visual function, macular hemorrhage may lead to amblyopia due to the delayed absorption caused by bleeding [2]. The risk factors and mechanisms underlying neonatal RH are not well-understood. While there are clinical studies reporting risk factor analyses of RH, there are no known systematic investigations of the correlation between the various risk factors and the degree of RH. To investigate risk factors associated with increases in RH for newborns, we performed a statistical analysis of the incidence and degree of RH in a large sample of full-term infants

Methods

Results

Conclusion