Risk factor of peritoneal dialysis-related infection: Impact of diabetes mellitus on long-term outcome

Abstract

laboratory findings, and outcome of the patients. Multilocus Sequencing Typing (MLST) was used to genotype the bacterial isolates to trace the relatedness of the isolates that caused bacteremia in newborn patients. The following clinical information and microbiologic data were collected: demographic characteristics, presence of central venous catheters, invasive diagnostic and therapeutic procedures, total parenteral nutrition (TPN) and intrafat, mechanical ventilation, and previous and current antibiotic exposure. Results: Forty cases with A. baumannii bacteremia were identified. Multidrug resistance was found in only four isolates (10%). The bacteremiarelated mortality rate is 7.5%. Most of the patients with A. baumannii infection had prolonged intubation, presence of percutaneous central venous catheter (PCVC) (65%) and longer use of TPN or intrafat (95%). The result of MLST showed diverse genotypes. Conclusions: A. baumannii bacteremia occurred primarily in preterm neonates on TPN and intrafat use and with prolonged intubation in the NICUs. A. baumannii bacteremia did not often lead to mortality and multidrugresistant A. baumannii is uncommon in neonatal patients. Decreasing the use of PCVC and intubation time could reduce the infection by A. baumannii in preterm neonates.