Abstract

Abstract: Neonatal sepsis is one of the causes of newborn death. Risk factors that can affect neonatal sepsis include maternal risk factors, infectious agent factors, infant risk factors and determinant factors. The purpose of this study was to determine and analyze the factors that influence the incidence of neonatal sepsis in the NICU room at the Naibonat Hospital, Kupang Regency. The design of this study used a case control research design (case control) with a retrospective study approach. The populations in this study were all newborns diagnosed with neonatal sepsis at the Naibonat Hospital, Kupang Regency from January to December 2020 totaling 85 cases. The sample size in this study was taken using a total sampling technique, where the entire population was used as a research sample, namely as many as 85 case samples, with a sample size ratio of 1:1 between cases and controls, so the total sample size was 170 samples. The results showed that maternal risk factors that significantly influenced the incidence of neonatal sepsis were premature rupture of membranes (p=0.020), Inpartum Fever (p=0.001), history of urinary tract infection (p=0.003) and length of parturition (p=0.006). For infectious agent factors that influence is bacteria (p = 0.009). For the baby risk factor that has an effect is the APGAR score (p = 0.000). Simultaneously, the most influential determinants on the incidence of neonatal sepsis were APGAR scores, labor duration and labor fever.

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