Risk assessment of peanut aflatoxins exposure by margin of exposure in China

Abstract

To explore the MOE(margin of exposure) application in risk assessment of peanut aflatoxins in consumers,data of aflatoxins contamination in post-harvest peanut of China and the data of Chinese peanut consumption were collected.Based on aflatoxins toxicological data,MOE values of different regions from population of different age-groups were evaluated.Results indicated no significant differences between urban and rural regions,but children were at higher risk than other populations.Compared to low-dose extrapolation,MOE was recommended due to its effective performance in posterior analysis.