Abstract

Since the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has continued to spread worldwide and has become a major global public health threat. SARS-CoV-2 has the characteristics of a long incubation period and asymptomatic infection, which are undoubtedly major challenges to blood transfusion safety. Although no research has suggested that there is a risk of SARS-CoV-2 transmission through blood transfusion, the safe use of clinical blood during the epidemic is a serious problem faced by blood collection and supply institutions. Herein, we elaborate on the management of blood collection and supply during the coronavirus disease 2019 (COVID-19) pandemic from aspects such as blood inventory management, clinical blood use, and reducing the risk of transmission of SARS-CoV-2 via blood transfusion. Blood service departments should adopt flexible policies to ensure that blood collection networks can meet clinical needs, while at the same time protecting staff and blood donors, maintaining blood safety, and reducing blood risks during the epidemic.

Highlights

  • The global outbreak of the coronavirus disease 2019 (COVID-19) is an immense challenge to public health [1]

  • No research has suggested that there is a risk of SARS-CoV-2 transmission through blood transfusion, the safe use of clinical blood during the epidemic is a serious problem faced by blood collection and supply institutions

  • Because there are currently no relevant data or blood transfusion infection cases that suggest that SARS-CoV-2 transmission is a risk of transfusion, the Food and Drug Administration (FDA) and the Center for Disease Control and Prevention have not yet published recommendations for blood collection and supply institutions

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Summary

Introduction

The global outbreak of the coronavirus disease 2019 (COVID-19) is an immense challenge to public health [1]. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mainly transmitted through respiratory tract fluids and physical contact, there is a possibility of aerosol transmission [2]. If volunteers donate blood during the incubation period, there is a risk of viral transmission to vulnerable patients, and this is undoubtedly a major challenge to current blood safety. There are major challenges in current blood collection and supply. Some recommendations for blood collection and supply management should be carefully discussed, including optimizing blood inventory and clinical blood management in some ways and reducing the risk of SARS-CoV-2 transmission through blood transfusion to ensure clinical blood safety

Blood Inventory Management under the COVID-19 Epidemic
Establishing an Early Warning Mechanism for Blood Inventories
Establishing a Blood Inventory Management Mechanism
Paying Attention to the Timing of Blood Distribution
Blood Transfusion Services during the Epidemic
Excluding High-Risk Blood Donors
Self-Protection of Staff
Reducing Pathogens in the Blood
Findings
Conclusion

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