Abstract

A prospective randomized study comparing trimethoprim sulfamethoxazole amoxicillin clavulanic acid and cefaclor was conducted on 47 children 12 boys and 35 girls in the treatment of acute urinary tract infection The patient s mean age was 4 7±4 0 years They were treated randomly for 10 days and followed up for at least one month Response to therapy and recurrence rates were evaluated There was no significant difference in the cure rates at 48 72 hours after the initiation and termination of the treatment between the groups On the other hand the recurrence rates were respectively 23 5 in the trimethoprim sulfamethoxazole 69 2 in the amoxcillin clavulanic acid and 42 5 in the cefaclor group within 2 weeks after the termination of the treatment and the high recurrence rate of amoxicillin clavulanic acid group was significant when compared to the trimethoprim sulfamethoxazole group During one year of follow up 20 of 31 patients had recurrence 64 5 and 80 of recurrence occurred within two weeks after the termination of treatment Key words: Bacteriuria Urinary Tract Infection Ultrasonography Voiding Cystoureterography

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