Abstract
Full thickness RV myocardial biopsies were taken during surgery in 21 patients with Tetralogy. Specimens stained with Trichrome and Verhoff VonGieson were analyzed. Grade I: Endocardial fibroelastosis with perivascular fibrous and collagen invasion. Grade II: Subendocardial collagen and fibroblast invasion with myocardial hypertrophy. Grade III: Myocardial cell disruption plus intimal thickening of intramural coronary arteries. Quantitative anglographic RV function was correlated with RV myocardial histology.
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