Right ventricular functions can predict left ventricular reverse remodeling in patients with ischemic cardiomyopathy after revascularization

Abstract

Background: Left Ventricular reverse remodeling is a major indicator of functional improvement in patients with ischemic cardiomyopathy undergoing revascularization. We aimed at investigating the ability of right ventricular functions to predict left ventricular reverse remodeling (LVRR) in those patients. Patients and methods: Subjects presented with ICM (n=52) were included and underwent right ventricular (RV) functions assessment. By the end of study patients were divided into two groups depending on positive LVRR response defined as ≥15% decrease in LV end-systolic volume (LVESV). Group 1 (n=28) with positive LVRR and group 2 (n= 24) without. Results: A significant difference between the two groups regarding right ventricular systolic tricuspid annular velocity (RV S'), RV myocardial performance index (RV MPI), RV free wall strain (RVFWS) and RV global longitudinal strain (RV GLS) was noticed. RV GLS was superior to RVFWS in prediction of LVRR (AUC difference of 0. 12, P=