Abstract
Background Cardiac MR (CMR) has emerged as the gold standard for assessing right-ventricular (RV) size and function with cine acquisitions. However, dyspnea often accompanies RV dysfunction, limiting patient ability to breathhold and consequently image quality at CMR. The application of a novel iterative reconstruction technique to segmented CMR cine acquisitions may enable higher acceleration factors, shortening image acquisitions, while maintaining image quality for RV assessment. The purpose of this study is to evaluate the clinical utility of a prototype iterative reconstruction algorithm utilizing spatio-temporal L1-regularization (iteratively reconstructed Sparse-SENSE) in the quantitative assessment of RV systolic function.
Highlights
Cardiac MR (CMR) has emerged as the gold standard for assessing right-ventricular (RV) size and function with cine acquisitions
The purpose of this study is to evaluate the clinical utility of a prototype iterative reconstruction algorithm utilizing spatio-temporal L1-regularization in the quantitative assessment of RV systolic function
Cine images were acquired in the 4-chamber and short-axis orientations using conventional generalized auto-calibrating partially parallel acquisition (GRAPPA) factor 2 acceleration ("GRAPPA 2”), a spatio-temporal undersampled TSENSE acquisition with factor 4 acceleration ("TSENSE 4”), and iteratively reconstructed Sparse SENSE with an acceleration factor of 4 ("IS-SENSE 4”)
Summary
Cardiac MR (CMR) has emerged as the gold standard for assessing right-ventricular (RV) size and function with cine acquisitions. Dyspnea often accompanies RV dysfunction, limiting patient ability to breathhold and image quality at CMR. The application of a novel iterative reconstruction technique to segmented CMR cine acquisitions may enable higher acceleration factors, shortening image acquisitions, while maintaining image quality for RV assessment. The purpose of this study is to evaluate the clinical utility of a prototype iterative reconstruction algorithm utilizing spatio-temporal L1-regularization (iteratively reconstructed Sparse-SENSE) in the quantitative assessment of RV systolic function
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