Right ventricle diastolic function in hypertensive patients

Abstract

Aim of this study were determination of correlation of changes of diastolic function of right (RV) and left ventricle (LV) in patients with essential arterial hypertension. 98 new founded hypertensives and 18 healthy volunteers were examined with pulse-wave Doppler echocardiography for determination of parameters of RV diastolic filling and connection between ones and diastolic function and remodeling of LV. We determined that positive correlation between isovolumic relaxation time in both ventricles increase with growth of LV myocardial mass: in patients with LV hypertrophy (n=36) r=0.67 (p<0.01) and in patients without one (n=62) r=0.48 (p<0.05). Correlation between early diastolic fraction of LV and RV was middle in patients with normal type and eccentric hypertrophy of LV (r=0.34, p<0.05) and strong in patients with concentric remodeling and concentric hypertrophy of LV (r=0.62, p<0.01). In control group we did not observe any connection between above mention parameters. Diastolic function of RV in hypertensives is impaired according to changes of LV's one. Correlation between filling of both ventricles is increased with growth of LV myocardial mass and concentric transformation. It can be explained with ones mechanisms of neuro-humoral regulation of myocardial remodeling (renin-angiotensin system etc.) and one middle and external layers of myocardium for both ventricles.