Abstract

Right-sided infective endocarditis (RSIE) is relatively rare, accounting for only 5 to 14% of all cases of infective endocarditis (IE). Its incidence is increasing due to the growing use of intravascular and intracardiac devices, as well as the rising prevalence of intravenous drug use. What distinguishes RSIE is that it often occurs on previously healthy valves. It can be associated with left-sided involvement (infective endocarditis with interventricular communication or complicated by septal perforation) or be limited to the valvular orifices of the right heart, more commonly affecting the tricuspid valve than the pulmonary valve. The diagnosis is established based on the Duke criteria. The prognosis can be poor, and the treatment primarily relies on antibiotic administration, with surgery reserved for specific indications related to vegetation size, hemodynamic issues, or infectious complications.

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