Abstract
Materials and methods Seventy three patients in mild or moderate stage of dementia of different types are included in the study. After a clinical interview with the patients and their relatives, the patients were divided into two groups: a) anosognosia consisted of 41 patients (mean age 73±11 y) (mean MMSE 17±5), who were not aware of their disease. b) no anosognosia including 32 patients (mean age 71±8 y) (mean MMSE 23±4), who had full awareness of their disorder. The patients underwent HMPAO single photon emission computed tomography (SPECT) and rCBF was measured using region of interest (ROI) in right and left prefrontal, frontal, superior and inferior parietal, lateral and medial temporal, occipital and Posterior cingulate.
Highlights
Anosognosia in patients with dementia may make the patients to behave unsafely and can have an impact on treatment compliance
The aim of this study is to evaluate the correlation of anosognosia in patients
moderate stage of dementia of different types are included in the study
Summary
Right inferior parietal region hypoperfusion as a reflection of anosognosia in dementia. Fereshteh Sedaghat*1,2, Anna Gotzamani-Psarrakou[2], Eleni Dedousi[2], Vassiliki Costa[1], Athanasios S Dimitriadis[3] and Stavros J Baloyannis[1]. Address: 1First Department of Neurology, AHEPA University Hospital, Thessaloniki, Greece, 2Department of Nuclear Medicine, AHEPA University Hospital, Thessaloniki, Greece and 3Department of Radiology, AHEPA University Hospital, Thessaloniki, Greece. Published: 17 April 2008 Annals of General Psychiatry 2008, 7(Suppl 1):S184 doi:10.1186/1744-859X-7-S1-S184. International Society on Brain and Behaviour: 3rd International Congress on Brain and Behaviour Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here.
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