Right atrial reservoir strain and right ventricular strain improves in patients recovered from hospitalisation for non-severe COVID-19

Abstract

Purpose Those hospitalised with coronavirus disease 2019 (COVID-19) have recently been shown to have impaired right ventricular (RV) strain, but data about the course of heart function after discharge are limited. Our aim was to compare right ventricular strain and right atrial reservoir strain (RASr) associated with COVID-19 between acute disease (during hospitalisation) and follow-up (after discharge). Methods In this retrospective single-center study, we analysed the echocardiograms of 43 patients hospitalised for non-severe COVID-19 between December 2020 and March 2021, undergoing echocardiography both during and after hospitalisation. In addition to conventional echocardiographic parameters, we applied 2-dimensional speckle tracking to obtain RV global longitudinal strain (RV-GLS), RV free wall strain (RV-FWS), and RASr. Results Mean (standard deviation) age of the study population was 50 (9) years, and 18 (42%) of the participants were women. Median duration between exams was 6 months (range, 5–7 months). Both mean RV-GLS and mean RV-FWS significantly increased at follow-up (−20.8 [3.8] vs. −23.5 [2.8], p < 0.001 and −23.3 [4.2] vs. −28.2 [2.8], p < 0.001; respectively), and RASr significantly improved as well (−32.3 [6.6] vs. −41.9 [9.8], p < 0.001). Conclusion In patients hospitalised for non-severe COVID-19 pneumonia, RV-GLS, RV-FWS, and RASr improved significantly between acute disease and 6 months after discharge.