Abstract
Right atrial pacing in patients with sinus node dysfunction results from an observational cohort study
Highlights
Sinus node dysfunction is characterized by one or more of the following electrocardiographic manifestations: sinus bradycardia, sinus arrest, sino-atrial block, and supraventricular tachycardia alternating with sinus bradycardia and asystole (Brady-tachycardia syndrome) [1]
Exclusion criteria were as follows: (i) ischemic heart disease; (ii) an left ventricular ejection fraction (LVEF)
85 patients were excluded because they fulfilled the following exclusion criteria: ischemic heart disease (n=21); an LVEF
Summary
Sinus node dysfunction is characterized by one or more of the following electrocardiographic manifestations: sinus bradycardia, sinus arrest, sino-atrial block, and supraventricular tachycardia alternating with sinus bradycardia and asystole (Brady-tachycardia syndrome) [1]. The presence of palpitations, dizziness, pre-syncope, or syncope associated with these electrocardiographic changes defines sinus node disease (SND). Paroxysmal atrial fibrillation (AF) is common in patients with sick sinus syndrome (SSS) and pacemakers, and leads to morbidity and an increased risk of stroke or death [6]. The recent DANPACE studyenrolled patients with SSS with no previous history of AF who received DDDR pacemakers [7,8], and aimed to determine the effect of atrial pacing on the occurrence of AF. This study did not find an association between increased atrial pacing and development of AF [7,8]
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